REJURAN®
KOREA’S LEADING SKIN BOOSTER1
REWRITE YOUR STORY
REJURAN® is a cutting-edge treatment originated in South Korea that has gained global recognition for its skin regeneration and anti-ageing properties. This innovative injectable therapy contains polynucleotides (PN), which are natural components found in salmon DNA.
Known for its for its ability to support the skin’s natural regeneration processes, REJURAN® promotes collagen production and skin rejuvenation, making it highly sought after by those looking to achieve smoother, firmer and more radiant skin2.
REGENERATIVE POWER OF POLYNUCLEOTIDES
HOW IT WORKS
Over time, our skin tells the story of our life. With age, it naturally loses moisture, firmness, and elasticity. Skin becomes thinner, drier, and more fragile. Fine lines, wrinkles, and visible pores start to appear and its ability to heal and regenerate slows down.
The polynucleotides used in REJURAN® are highly purified DNA fragments derived from wild salmon. They are biocompatible – meaning they work safely with human skin – and their structure helps the skin restore itself3.
Once injected, polynucleotides act like a “repair signal” inside the skin. They attract water to deeply hydrate the tissues and create an ideal environment for skin cells to regenerate. They also support fibroblasts – the cells that produce collagen and elastin – helping the skin become smoother, firmer, and healthier over time4.
OVERALL SKIN QUALITY IMPROVEMENT
PATENTED DOT™ TECHNOLOGY5
REJURAN® PN-based injectable gels are manufactured using PharmaResearch’s patented DNA Optimizing Technology (DOT™) to obtain purified polynucleotide (PN) and polydeoxyribonucleotide (PDRN) materials.
What makes DOT™ Technology different?
- The use of wild Oncorhynchus keta (O. keta) as a raw source.
- Manufacturing DNA fragments within defined molecular characteristics.
- Quality controlled production of final products.
- Application of DNA fragments to various product categories.
PN and PDRN products manufactured through DOT™ have been utilised in clinical practice for more than 10 years, with multiple published studies supporting their use in various aesthetic and medical applications5,6.
SKIN REPAIR & REJUVENATION
THE BENEFITS OF REJURAN® TREATMENT2
Boosted skin glow
Improved skin quality
Reduced fine lines & wrinkles
Acne scars smoothed out
Tightened pores
KEY FACTS
One of the leading PN-based skin boosters in Korea1
CE MDR certification obtained in 2024
Present in more than 50 countries
More than 15 million syringes used since its first launch in 2014
30 years of research in regenerative science
FAQ2
Is REJURAN® the same as a dermal filler?
REJURAN® has a different mode of action. It works at a cellular level to stimulate the skin’s natural regeneration.
Is REJURAN® right for me?
REJURAN® may be a good option if you want to improve overall skin quality, including hydration, smoothness, firmness, and radiance. It is suitable for many skin types and is often chosen by patients looking to address fine lines, enlarged pores, mild scarring, or dullness, Your aesthetic practitioner will assess your skin and goals to confirm whether REJURAN® is the right treatment for you.
What does the treatment involve?
The procedure typically consists of a series of small, superficial injections performed by your practitioner. The most common protocol includes 3 sessions spaced out by ~1 month. However, multiple sessions may be recommended for the best results. During your consultation, your aesthetic physician will help to choose the right protocol depending on our skin condition and concerns.
When will I see results?
Most patients notice an improvement in skin texture and radiance after 2–4 weeks, with progressive results after multiple sessions.
Is it safe?
Yes. REJURAN® is biocompatible and has been clinically tested for safety and efficacy.
Can it be combined with other treatments?
Yes. Your practitioner may combine REJURAN® with dermal fillers, lasers, or skin boosters for optimal results.
How long do results last?
Up to 6–12 months, depending on your skin condition and maintenance.
READY TO EXPERIENCE SKIN REGENERATION WITH REJURAN®?
- PharmaResearch Internal Data.
- REJURAN IFU (EN, FR) 251029.
- Hites RA, Foran JA, Schwager SJ, Knuth BA, Hamilton MC, Carpenter DO. (2004). Global assessment of polybrominated diphenyl ethers in farmed and wild salmon. Environmental Science and Technology, 38(19), pp4945-4949.
- Lee KWA, Chan KWL, Lee A, et al. Polynucleotides in aesthetic medicine: a review of current practices and perceived effectiveness. Int J Mol Sci. 25(15). doi:10.3390/ijms25158224.
- Patent No.: 10-0986603.
- Pak CS, et al. A Phase III, Randomized, Double-Blind, Matched-Pairs, Active-Controlled Clinical Trial and Preclinical Animal Study to Compare the Durability, Efficacy and Safety between Polynucleotide Filler and Hyaluronic Acid Filler in the Correction of Crow’s Feet: A New Concept of Regenerative Filler. J Korean Med Sci. 2016 Feb 31(2):330-330.
REJURAN®, REJURAN® I, and REJURAN® S are Class III medical devices, regulated health products bearing the CE marking (CE 2265). REJURAN®, REJURAN® I, and REJURAN® S are intended to promote tissue restoration and reconstruction, as well as the improvement of physical appearance on the face, neck, décolleté, and hands. These products are only to be administered by appropriately trained healthcare professionals who are qualified or accredited in accordance with national law. Consult the IFU before injection. Any serious side effects occurring in relation to the product should be reported without delay to Laboratoires VIVACY (customer.complaint@vivacy.fr) and to the national health authority of the country in which the patient is established. Manufacturer: PharmaResearch 77-19, Gwahakdanji-ro, Gangneung-si, Gangwon-do, Korea.